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The sequence identity of CYP A with CYP A
2020-08-21

The sequence identity of CYP3A163 with CYP3A sequences from other species is maximum in reptiles ranging (75-91)%, gradually decreasing from Fosmidomycin sodium salt (63-71)% to mammals 62% to downwards based on evolutionary distances. The high level of homology with CYP3A77 in Alligator mississippi
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br System description and data collection Fig shows the arra
2020-08-21

System description and data collection Fig. 1 shows the arrangement of the system studied. It provided cooling β-Tocotrienol to maintain thermal conditions in an institutional building. The locations of the measured variables (, and ) relating to temperature and flow rate are indicated in Fig. 1
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br Overall system architecture In
2020-08-21

Overall system architecture In this WP1130 section we provide a description of the system under study, and its surrounding environment, on an “as is” basis. The architecture presented in the following is the one currently adopted on-field by ASTS (e.g., at Rome train station). The Train Managem
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Immunology Compound Library receptor Although BPA has been p
2020-08-21

Although BPA has been proven to cause many health issues such as obesity and neurological toxicity (Rubin, 2011), the effects and mechanisms of BPA on the human tumorigenesis and cancer development are still not well illustrated. In the present study, we found that 10 to 10M BPA significantly promot
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As for the molecular mechanism Ferguson BD
2020-08-21

As for the molecular mechanism, Ferguson BD suggested that EphB4/EphrinB2 stimulation induced topoisomerase I activity in small cell lung cancer cell lines. Treatment of biotin 100 mg with EphrinB2/Fc induced topoisomerase activity as assessed by DNA relaxation in cells with high EphB4 expression l
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br Introduction Pattern separation is the ability to
2020-08-20

Introduction Pattern separation is the ability to make distinct representations from highly overlapping information, a process which is important for memory encoding (Clelland et al., 2009). For correct pattern separation, old information needs to be retrieved and compared to new information. If
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Saito et al reported that d http www apexbt
2020-08-20

Saito et al. reported that diabetic bone has lower lysyl oxidase-derived enzymatic cross-links in collagen compared to non-diabetic bone, based on studies performed in a rat model [9]. Lysyl oxidase plays a pivotal role in bone development and function, as revealed in classical studies [10], [11]. L
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It is well known that CysLTs exert potent
2020-08-20

It is well known that CysLTs exert potent contractile action on human bronchial smooth muscles through activation of CysLT1 receptors. Indeed, in vitro antigen-induced contraction of passively sensitized human bronchial tissue is markedly suppressed by a pre-treatment with CysLT1 receptor antagonist
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Proteases as multifunctional enzymes play key roles
2020-08-20

Proteases, as multifunctional enzymes, play key roles in controlling a wide variety of cellular and extracellular processes in plants and animals, including protein degradation and processing, germination, complement activation, inflammation, responses to environmental stimuli, senescence and so on.
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br Conflict of interest statement br
2020-08-20

Conflict of interest statement Acknowledgement The study was financially supported by the Ministry of Education, Youth and Sports of the Czech Republic – projects “CENAKVA” (No. CZ.1.05/2.1.00/01.0024) and “CENAKVA II” (No. LO1205 under the NPU I program), by the Grant Agency of the University
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CXCL mediated cell migration is facilitated by the interacti
2020-08-20

CXCL16 mediated cell migration is facilitated by the interaction of soluble CXCL16 with CXCR6, expressed predominantly on the cell surface of CD4+ Th1 cells, cancer infiltrating lymphocytes and platelets (Borst et al., 2012, Kim et al., 2001, Liao et al., 1997, Wilbanks et al., 2001). CXCR6 is invol
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The large body of structural knowledge that
2020-08-20

The large body of structural knowledge that is currently available for CRM1 has contributed to atomic level and mechanistic understanding of many steps in the CRM1 nuclear export cycle. However, structural analysis could still inform on several outstanding questions and guide future discoveries pert
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Introduction Klebsiella pneumoniae a Gram negative enteric
2020-08-20

Introduction Klebsiella pneumoniae, a Gram-negative enteric bacterium, is an organism with significance in both biomedicine and biotechnology. Some of the strains of K. pneumoniae are opportunistic pathogens, which can cause suppurative infection, pneumoniae and urinary tract infection in humans (B
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The aim of the present study was to investigate the
2020-08-20

The aim of the present study was to investigate the acute effects of THC on resting state MK-4827 Racemate neurophysiology, and to examine the impact of COMT genotype on these effects. Thirty-nine healthy volunteers participated in a randomised, placebo-controlled, crossover pharmacological MRI stu
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Theoretically the expression profile of GluCl variants was r
2020-08-20

Theoretically, the expression profile of GluCl variants was related to their physiological roles. It was reported that all the three variants (GluCl A, GluCl B, GluCl C) were highly expressed in head tissue of L. striatellus and M. domestica, and the expression level of GluCl A was significantly hig
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