• The different diagnostic outcomes of the two assays

  2020-10-22

  

  The different diagnostic outcomes of the two assays are also dependent on the used stimuli. The QuantiFERON-CMV assay targets CD8 + T Bromoenol lactone synthesis by using peptides whereas the T-Track-CMV targets CD4+ and CD8 + T cells by stimulation with two viral proteins [18]. In our study, a sp

• Among the different factors that modulate Schwann cell biolo

  2020-10-22

  

  Among the different factors that modulate Schwann cell biology, several studies pointed out the role played by neuroactive steroids, in particular progesterone (P4) and its derivatives dihydroprogesterone (DHP) and allopregnanolone (ALLO). Schwann Gardiquimod are steroidogenic, possessing the entir

• Primary renal PNET was first reported

  2020-10-22

  

  Primary renal PNET was first reported by Seemayer et al in 1975. The possible etiology of rPNET is based on the theory of neural cell intussusception in the kidney during development that initiates the tumorigenesis. rPNET most commonly affects young adults, with a mean age of 30.4 years and male pr

• Among the down regulated genes were several of

  2020-10-22

  

  Among the down-regulated genes were several of interest. Coronin2a (Coro2a), a component of the nuclear receptor co-repressor complexes, contributes to de-repression of inflammatory response genes (Huang et al., 2011). Mill1, an MHC family member expressed in hair follicles, represses wound healing

• TgTCEA from petals TgTCEA and TgTCEB

  2020-10-22

  

  TgTCEA from petals (TgTCEA1) and TgTCEB from pollen grains (TgTCEB1) were used throughout the study. The recombinant enzymes were expressed in , and purified as the His-tag-free forms as described previously., Enzyme reactions were performed at 4 mM substrates under the same conditions as described

• br Materials and methods br

  2020-10-22

  

  Materials and methods Results Discussion DNA-PKcs and the Ku heterodimer (Ku70 and Ku80) constitute the DNA-PK complex, which is a serine/threonine kinase. DNA-PK phosphorylates H2AX and other substrates, such as main NHEJ factors (Artemis, XRCC4, and DNA ligase IV) [4]. Therefore, DNA-PK d

• br Materials methods br Results and discussion The compariso

  2020-10-22

  

  Materials & methods Results and discussion The comparison of BFI methods (Table 1) shows that Phosphatesmo failed to detect seminal fluid in all samples. This observation is concordant with other studies that investigated water-exposed seminal fluid stains [6], [7]. The Phosphatesmo test is us

• br Materials and methods br Results br Discussion To

  2020-10-22

  

  Materials and methods Results Discussion To date, several reports have suggested an involvement of DGK in bipolar disorder. A splice variant at the COOH-terminus of DGKβ has been related to bipolar disorder [15] and DGKβ KO mice showed hyperactive behavior [17]. For the other DGK isoforms,

• In conclusion over expression of Stokesia epoxygenase SlEPX

  2020-10-22

  

  In conclusion, over-expression of Stokesia epoxygenase (SlEPX) in soybean seeds led to some unusual seed phenotypes. These effects can be overcome by coexpression of Vernonia DGATs (VgDGAT1 & 2). The DGATs can specifically transfer vernolic Bosutinib into TAG, largely reducing vernolic acid levels i

• DAPK is a kD Ca

  2020-10-22

  

  DAPK is a 160-kD Ca2+/calmodulin (CaM)-regulated Ser/Thr kinase that mediates cell death. The activated forms of DAPK and DRP-1 are capable of inducing two distinct cytoplasmic events characteristic of programmed cell death, including membrane blebbing and the formation of autophagic vesicles (Inba

• We neither observed changes in midazolam eCLmet indicative o

  2020-10-21

  

  We neither observed changes in midazolam eCLmet indicative of significant inhibition of CYP3A4/5 during both experiments, despite the in vitro evidence for CYP3A4/5 inhibition (Theile et al., 2017). The observed increase in CYP3A dependent midazolam clearance after chronic ingestion of clementines/c

• Among prostaglandins PG PGD remained the most elusive

  2020-10-21

  

  Among prostaglandins (PG), PGD2 remained the most elusive species for a long time and was initially regarded as having negligible biological activity [1]. In 1974 its inhibitory effect on platelet aggregation was discovered by Smith et al. [2] and Mills & McFarlain [3], and both pressor and depresso

• BG45 Allele specific methylation has been observed in CpG

  2020-10-21

  

  Allele-specific methylation has been observed in CpG islands of imprinted genes.27, 32 In the present study, however, methylation of CpG1 was specific to ALL BG45 and occurred in the leukemia cells of 28% of children with ALL, but it was not found in normal leukocytes from the same patients. Methyla

• The in vitro cytotoxicity of

  2020-10-21

  

  The in vitro cytotoxicity of the prodrugs was assessed in the LS174T human colon cell line (). The results were found to reflect the stability of the prodrugs, with the unstable urea compounds ( and ) giving relatively poor cytotoxicity differentials between prodrugs and parents (i.e., approximately

• oicr australia Previously we have shown that complexes of

  2020-10-21

  

  Previously, we have shown that complexes of protein PKs with inhibitors that comprised sulfur or selenium atoms in aromatic structures were phosphorescent at room temperature, while the long-lifetime signal emitted by the free inhibitor was negligible.34, 35, 36 This phenomenon was caused by stabili

11046 records 458/737 page Previous Next First page 上5页 456457458459460 下5页 Last page